Scientific News by Teresa Binstock

News on vaccines, environmental pollutants, and susceptibility.

http://www.generationrescue.org/binstock/index.htm

Teresa posts alot of helpful research and news to various groups on the internet – join some of the communities on the right side of this page to read her posts.

Hertz-Picciotto’s blood mercury autism study: what the researchers omitted

Hertz-Picciotto’s blood mercury autism study: what the researchers omitted

Teresa Binstock
Researcher in Developmental & Behavioral Neuroanatomy
October 21, 2009

Irva Hertz-Picciotto & colleagues have published results of a study comparing mercury (Hg) levels in children with and without autism (1). The study does not report findings about total body burden of Hg in children, nor does the study evaluate levels of Hg in the brain or other specific organs in autistic and non-autistic children.

Indeed, the researchers who did the blood-Hg study state: “As only 5% of body burdens of Hg are estimated to be in circulation, (Burbacher et al. 2005; Stinson et al. 1989) reliable conclusions about distribution are not possible from one-time observational measurements in blood.” (1) Since various forms of mercury can enter the brain and remain there (17), and since different tissues of humans and other species retain mercury at various rates (16), the larger context of Hertz-Picciotto et al’s findings need be considered.

Relevant questions include: What do Hg levels in blood signify? Alternatively, what don’t they signify? And what does intra-body and intra-brain mercury mean for children with weak alleles in glutathione-related pathways or born to mothers with weak alleles in glutathione-related pathways?

Although the new study purports to offer a review of autism genetics, Hertz-Picciotto et al (1) omit an important category of citations related to mercury, glutathione, methylation, and autism (eg, 2-14).

Furthermore, the researchers cite two studies of in vivo thimerosal levels (Pichichero et al 2002, 2008) while omitting consideration of Waly et al 2004, who investigated thimerosal levels lower than those described by Pichichero et al 2002 in human infants, found that methionine synthase was inhibited, and concluded that “The potent inhibition of this pathway by ethanol, lead, mercury, aluminum and thimerosal suggests that it may be an important target of neurodevelopmental toxins.” (15)

Why were these important findings omitted? Weren’t the reviewers aware of cites 1-15 hereinbelow?

In seeking to understand intra-body and intra-brain Hg, Lorscheider et al provide important insights.

In a study available free online, data reviewed by Lorscheider et al (16) indicate that Hg exposure does not lead to equivalent concentration in all tissues. For instance, from chronic exposure via amalgam vapors, some tissues accumulate more Hg than do other tissues (16).

Caveat: ingesting one’s own amalgam vapors probably includes olfactory exposure as well as oral/gastrointestinal exposure and therefore is not perfectly akin to ingesting Hg by eating fish. Nonetheless, Hg distribution findings due to amalgams may be instructive.

“The degree to which body tissues can sequester amalgam Hg after exposure has been demonstrated in a variety of human and animal experiments… The brain/CSF Hg ratio had increased threefold by 4 wk after amalgam fillings had been installed…” (16)

“Repeated observations in adult sheep… demonstrate that after placement of amalgam fillings the blood Hg levels remain relatively low even though the surrounding body tissue concentrations of Hg become many fold higher than blood. This suggests that tissues rapidly sequester amalgam Hg at a rate equivalent to its initial appearance in the circulation. Such a phenomenon may explain why monitoring blood levels of Hg in humans is a poor indicator of the actual tissue body burden directly attributable to continuous low-dose Hg exposure from amalgam.” (16)

Lorscheider et al (16) summarize another important point:

“Both intracellular Hg2 and Hg are ultimately bound covalently to glutathione (GSH) and protein cysteine groups. Hg2 is the toxic product responsible for the adverse effects of inhaled Hg0. Body tissues have various retention half-lives for Hg and Hg2 ranging from days to years… ”

Implications ensue from the Hg/GSH genetics findings in autism and from the Hg-distribution studies reviewed in Lorscheider et al:
a) Tissue levels of Hg are are likely differ from and to be greater than Hg levels found in blood.
b) Subgroups of children who have developed autism are known to have one or more problems in pathways related to glutathione and methylation (eg, 2-14) may detoxify Hg and related compounds poorly and thus may sequester Hg and related compounds disadvantegeously.
c) Blood levels of Hg in autistic children (1) tell us little about Hg in their brain and other tissues.

As Hertz-Picciotto et al mention, several studies have found associations between autism rates and environmental mercury (18-20), and these findings conjoin with the often ignored fact that thimerosal in early life vaccines increases risk for autism and for developmental disabilities requiring special education (21-22).

Be aware: some brands of H1N1 (“swine”) flu vaccine and non-H1N1 influenza vaccines contain substantial amounts of thimerosal (eg, 23).

1. Blood Mercury Concentrations in CHARGE Study Children with and without Autism
Irva Hertz-Picciotto et al.
http://www.ehponline.org/members/2009/0900736/0900736.pdf

2: James SJ et al. Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism. FASEB J. 2009 Aug;23(8):2374-83.

3: James SJ et al. Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism. Am J Clin Nutr. 2009 Jan;89(1):425-30.

4: James SJ et al. Abnormal transmethylation/transsulfuration metabolism and DNA hypomethylation among parents of children with autism. J Autism Dev Disord. 2008 Nov;38(10):1966-75.

5: James SJ et al. Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism. Am J Med Genet B Neuropsychiatr Genet. 2006 Dec 5;141B(8):947-56.

6: James SJ et al. Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am J Clin Nutr. 2004 Dec;80(6):1611-7.

7: Deth R et al. How environmental and genetic factors combine to cause autism: A redox/methylation hypothesis. Neurotoxicology. 2008 Jan;29(1):190-201.

8: Westphal GA et al. Homozygous gene deletions of the glutathione S-transferases M1 and T1 are associated with thimerosal sensitization. Int Arch Occup Environ Health. 2000 Aug;73(6):384-8.

9: M?ller M et al. Inhibition of the human erythrocytic glutathione-S-transferase T1 (GST T1) by thimerosal. Int J Hyg Environ Health. 2001 Jul;203(5-6):479-81.

10. Williams TA et al. Risk of autistic disorder in affected offspring of mothers with a glutathione S-transferase P1 haplotype. Arch Pediatr Adolesc Med. 2007 Apr;161(4):356-61

11. Geier DA et al. Biomarkers of environmental toxicity and susceptibility in autism. J Neurol Sci. 2009 May 15;280(1-2):101-8.

12. Ming X et al. Genetic variant of glutathione peroxidase 1 in autism. Brain Dev. 2009 Feb 3. [Epub ahead of print]

13. Al-Gadani Y et al. Metabolic biomarkers related to oxidative stress and antioxidant status in Saudi autistic children. Clin Biochem. 2009 Jul;42(10-11):1032-40.

14. Pasca SP et al. One Carbon Metabolism Disturbances and the C667T MTHFR Gene Polymorphism in Children with Autism Spectrum Disorders. J Cell Mol Med. 2008 Aug 9.

15. Waly M et al. Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal. Mol Psychiatry. 2004 Apr;9(4):358-70.

16. Lorscheider FL et al. Mercury exposure from “silver” tooth fillings: emerging evidence questions a traditional dental paradigm. FASEB J. 1995 Apr;9(7):504-8.
http://www.fasebj.org/cgi/reprint/9/7/504

17. Burbacher TM et al. Comparison of blood and brain mercury levels in infant monkeys exposed to methylmercury or vaccines containing thimerosal. Environ Health Perspect. 2005 Aug;113(8):1015-21.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280342/pdf/ehp0113-001015.pdf

18. Palmer RF et al. Environmental mercury release, special education rates, and autism disorder: an ecological study of Texas. Health Place. 2006 Jun;12(2):203-9.

19.Windham GC et al. Autism spectrum disorders in relation to distribution of hazardous air pollutants in the san francisco bay area. Environ Health Perspect. 2006 Sep;114(9):1438-44.

20. Palmer RF et al. Proximity to point sources of environmental mercury release as a predictor of autism prevalence. Health Place. 2009 Mar;15(1):18-24.

21. Hepatitis B vaccination of male neonates and autism
[conference abstract as published]
CM Gallagher, MS Goodman, Graduate Program in Public
Health, Stony Brook University Medical Center, Stony Brook, NY
Annals of Epidemiology, p659
Vol. 19, No. 9 Abstracts (ACE) September 2009: 651?680
[triple the rate of autism among boys vaccinated with thimerosal versus boys not so vaccinated]

22. Hepatitis B triple series vaccine and developmental disability in US children aged 1-9 years
Gallagher C, Goodman M. Toxicol Environ Chem 2008 90(5):997-1008.
{free online}
http://fourteenstudies.org/pdf/hep_b.pdf

“The odds of receiving EIS were approximately nine times as great for vaccinated boys… as for unvaccinated boys…, after adjustment for confounders.

23. H1N1 Vaccines Approved: What’s In It For You?
By Jackie Lombardo
http://nontoxicchildhood.blogspot.com/2009/10/h1n1-vaccines-approved-whats-in-it-for.html

Contact Teresa Binstock by email

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Autism Speaks Annual Report

Before you put on your walking shoes, let’s take a look at Autistm Speaks Annual Report, shall we? Make sure you open the link, so you can read along with me, okay? Thanks.

http://www.autismspeaks.org/annual_report.php

Click on the 990 pdf from 2008. Here’s a direct link:
http://www.autismspeaks.org/docs/Autism_Speaks_Form_990_2008.pdf

Reported Salaries:
Mark Roithmayr: $400,413.00
Peter Bell: $265,981.00
Geri Dawson: $669,751.00 (plus her HUGE relocation package)
Alison Singer: $201.942.00
Glen Tringali: $255,256.00
The list goes on and on…..

Credit card fees and bank charges: $989,344.00 (Yes folks, almost ONE MILLION DOLLARS in CREDIT CARD FEES and BANK CHARGES)

Office Expenses: $3,902,682.00 – yes, they spent almost FOUR MILLION DOLLARS on office expenses. And over a million dollars on rent on their swanky office digs at 2 Park Avenue in New York, NY.

Geri Dawson’s Relocation cost: $269,721.00 (page 55) – Almost THREE HUNDRED THOUSAND DOLLARS for her to relocate?

These are merely a few of the expenditures that truly made me sick to my stomach.

If you want to walk or donate, do it for a cause which will actually help children with autism – here are a few suggestions:
NVIC’s Vaccinated vs Unvaccinated Study: https://secure.groundspring.org/dn/index.php?aid=22354
TACA: http://www.talkaboutcuringautism.org/index.htm
Generation Rescue: http://generationrescue.org/
Lend4Health: http://lend4health.blogspot.com/

Autism: The New Gold Rush from Schmuck Roaster on Vimeo.

European Children Better Protected Than US Children

European Children Better Protected than US Children: An Outrage

Did you know that Kraft Macaroni and Cheese is formulated differently in Europe than that in the U.S.? This fact recently surfaced while I was doing an investigative search, I was livid!

I’ve been teaching, lecturing, and reporting about the dangers of food additives for over 15 years, and to think that other countries have been successful in forcing manufacturers to remove harmful ingredients, and in the U.S. we haven’t been, is mind-boggling.

In 2008, Kraft removed artificial colorings, like yellow#5 and chemical sweeteners like aspartame, from the products they distribute in Europe, Australia, and other developed countries. This occurred due to consumer concern over the scientific link of these synthetic ingredients to hyperactivity and asthma in children, and a myriad of other health disorders too numerous to mention in this context – why hasn’t the U.S. done the same?

Thanks to organizations like MomsRising, a petition has been started to write Irene Rosenfeld, CEO of Kraft Foods and a mother of two, requesting Kraft Foods remove these same ingredients from their U.S. products.

The letter campaign simply requests that Kraft value the health of our children as highly as they value children in other countries.

Together, we CAN make a difference, get involved.

Here’s the link to sign the letter. Complacency leads to Complicated Invisible Disorders – are you willing to take the responsibility of illnesses in your children and others that you could have prevented by adding your voice? Be proactive before a disorder emerges and you’re forced to become reactive?

I salute MomsRising for practicing what they teach….involvement and education to make a healthy difference – naturally.

Your Partner in Health,

Dr. Gloria Gilbere (aka Dr. G), N.D., D.A.Hom., Ph.D., EcoErgonomist, Wholistic Rejuvenist

Creator of certificated courses for health professionals to become Wholistic Rejuvenists. Visit my website at www.gloriagilbere.com. Sign-up for my free weekly Blog on www.yourhealthdetective.com.

Treating the FLU Naturally & Prevention of the Swine Flu

Written by Defeat Autism Now provider, Marcella Piper-Terry

http://4allofyou.blogspot.com/2009/10/treating-flu-naturally-priceless.html

“Treating the flu without worrying about Mercury or Squalene from vaccinations: Priceless.”

Another great post by Marcella, Sambucol Good for Prevention BUT NOT treatment of the H1N1 Flu:
http://4allofyou.blogspot.com/2009/10/sambucol-good-for-prevention-but-not.html

Judge Halts FLU Vaccine Mandate for Health Workers

Judge Halts Flu Vaccine Mandate For Health Workers
New York Health Care Employees Won’t Be Forced To Get H1N1 Vaccine…For Now

Health care workers in New York will no longer be forced to get the H1N1 swine flu vaccine, CBS 2 has learned.

A state Supreme Court judge issued a restraining order Friday against the state from enforcing the controversial mandatory vaccination.

The order came as the Public Employees Federation sued to reverse a policy requiring vaccination against the seasonal and swine flu viruses, arguing that state Health Commissioner Richard Daines overstepped his authority.

Three parties – the Public Employees Federaion, New York State United Teachers, and an attorney representing four Albany nurses – challenged the order and for now the vaccination for nurses, doctors, aides, and non-medical staff members who might be in a patient’s room will remain voluntary.

The health department had said the workers must be vaccinated by November 30 or face possible disciplinary action, including dismissal. PEF said it encourages members to get flu vaccinations, but opposes the emergency regulation requiring the vaccine as a condition of employment.

A judge granted a temporary restraining order Friday morning, PEF spokeswoman Debbie Miles said. A court hearing is scheduled for October 30.

New York was the first state in the country to initially mandate flu vaccinations for its health care workers, but many health care workers quickly protested against the ruling. In Hauppauge, workers outside a local clinic screamed “No forced shots!” when the mandate came down at the end of September.

“I don’t even tend to the sick. I am in the nutrition field. They are telling me I must get the shot because I work in a health clinic setting,” said Paula Small, a Women, Infants and Children health care worker.

Small said she would refuse to be vaccinate, worried the vaccine is untested and unproven, leaving her vulnerable. In 1976, there were some deaths associated with a swine flu vaccination.

Registered nurse Frank Mannino, 50, was also angry. He said the state regulation violates his personal freedom and civil rights.

“And now I will lose my job if I don’t take the regular flu shot or the swine flu shot.”

When asked if he’s willing to lose his job, Mannino said, “Absolutely. I will not take it, will not be forced. This is still America.”

The protest also shook Albany. Hundreds of demonstrators demanded freedom of choice. After all, as health care professionals, they argue they’re already constantly washing their hands and aren’t likely to transmit or contract the flu.

Around 500,000 health care workers would have been slated to receive the vaccine

“It’s certainly their prerogative to voice their opinion,” said Dr. Susan Donelan of Stony Brook University Hospital.

Donelan said most in the medical community see the benefits and safety of the shots and welcome them, and that hospitals must obey the law.

“Our hospital is committed to following the mandate to have our personnel vaccinated,” she said.

The state said change was needed this year to save lives. Typically only about 45 percent of health care workers take advantage of voluntary flu vaccines.

More than 150 institutional outbreaks of seasonal and H1N1 flu are expected this year in hospitals, nursing homes and hospice centers.

There is also a strong resistance to the vaccine from the general public. A new Harvard University poll shows that only four in 10 adults intend to take the vaccine themselves, and only six in 10 plan to give it to their children.

A quote you may never forget…

Quote From Marcia Angell MD is a well-known, respected physician, long-time editor of NEJM.

It is simply no longer possible to believe much of the clinical research that is published, or to rely on the judgment of trusted physicians or authoritative medical guidelines. I take no pleasure in this conclusion, which I reached slowly and reluctantly over my two decades as an editor of The New England Journal of Medicine.

http://e-patients.net/archives/2009/10/a-quote-i-wont-soon-forget.html

Dr. Mercola: Vitamin D3 kills H1N1

Thanks Dr. Mercola!

NaturalNews.com: Esteemed virologist Dr Albert Osterhaus accused of stoking pandemic fears to promote his own vaccine business interests

NaturalNews.com: Esteemed virologist Dr Albert Osterhaus accused of stoking pandemic fears to promote his own vaccine business interests

(NaturalNews) In the world of virology, few people have the track record of achievements attributed to Dr. Albert Osterhaus. He’s the Head of Department of Virology at the Erasmus MC, University of Rotterdam. Among his many achievements, he was the first to prove the infection mechanism of SARS in 2003. He’s also credited with being the first to detect the cross-species infection mechanism of H5N1.

In his 20 years of dedication to the study of infectious disease, Dr. Osterhaus has authored more than 650 scientific papers and is credited with the identification of a dozen viral pathogens. To anyone who works in any scientific field, these are astonishing achievements.

Dr. Osterhaus’s credentials and expertise in his field aren’t in question. What’s being scrutinized now, according to a short report published by the journal Science, are his links to corporate interests that stand to potentially profit from the swine flu pandemic.

According to a European Commission “Research” website, Dr. Osterhaus is the co-founder of two biotech companies, and is involved in promoting vaccines as a solution against a future pandemic. As published on the Science website:

Read more here:
http://www.naturalnews.com/027279_pandemic_swine_flu.html

Bill Maher on Vaccines

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